NCR2 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-16313-60, E-AB-16313-120, E-AB-16313-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: NCR2

Target Synonym: Activating NK receptor NKp44; CD336; CD336 antigen; dJ149M18.1; LY95; Lymphocyte antigen 95 (activating NK receptor; NK p44); Lymphocyte antigen 95 homolog (activating NK receptor; NK p44); Lymphocyte antigen 95 homolog; Lymphocyte antigen 95; mouse; homolog of; Natural cytotoxicity triggering receptor 2; Natural killer cell p44 related protein; Natural killer cell p44-related protein; NCR2; NCTR2; NK cell activating receptor (NKp44); NK cell activating receptor; NK cell-activating receptor; NK p44; NK-p44; NKp44

Research Areas: Cancer, Immunology, Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: O95944

Background: Natural cytotoxicity triggering receptor 2is aproteinthat in humans is encoded by theNCR2gene. NCR2 has also been designated asCD336(cluster of differentiation336). NKp44 is a natural cytotoxicity receptor that is is expressed on IL-2-activated human NK cells and may contribute to the increased efficiency of NK cells to mediate tumor cell lysis. NKp44 is composed of one Ig-like extracellular domain, a transmembrane segment, and a cytoplasmic domain. Prolactin up-regulates and cortisol down-regulates the surface expression of NKp44 at the transcriptional level. A cellular ligand for NKp44 (NKp44L) is expressed during HIV-1 infection and is correlated with the progression of CD4+ T cell depletion and an increase of viral load.

Concentration: 0.7 mg/mL

Immunogen: Synthetic peptide of human NCR2

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only